The 21st International Conference on Information Systems Security (ICISS 2025) will be hosted by IIT Indore from December 16-20, 2025. ICISS is a premier international conference on information security and privacy. The ICISS conference provides a dynamic platform for researchers, academicians, and industry professionals worldwide to discuss and explore advancements in cybersecurity, cryptography, system security, and hardware security. Since its inception in 2005, the conference has fostered impactful research collaborations, addressing emerging security challenges in computing and information systems. With keynote talks by leading experts, technical paper presentations, hands-on workshops, and panel discussions, ICISS 2025 aims to facilitate knowledge exchange and shape the future of digital security. As the host of ICISS 2025, the Indian Institute of Technology Indore (IIT Indore) stands at the forefront of technological research and academic excellence. Established in 2009, the institute has rapidly gained recognition for its pioneering contributions in engineering, science, and interdisciplinary fields, including cybersecurity and information systems. With a distinguished faculty, world-class research facilities, and strong industry collaborations, IIT Indore provides an intellectually stimulating environment for innovation and discovery. Its scenic campus and state-of-the-art infrastructure make it an ideal venue for an international conference of this caliber, ensuring an enriching experience for all participants. For more details: https://iciss.isrdc.in/ Important Dates Submission Deadline: Regular: July 25, 2025 Industry/Demo: August 10, 2025 PhD Forum: October 10, 2025 Tutorials: October 10, 2025 Acceptance Announcement Regular: September 30, 2025 Industry/Demo: September 30, 2025 PhD Forum: October 30, 2025 Tutorials: October 30, 2025 Camera-Ready Regular: October 15, 2025 Industry/Demo: October 15, 2025 PhD Forum: November 10, 2025 Tutorials: November 10, 2025 atron Suhas S. Joshi, IIT Indore, India General Chair R. K. Shyamasundar, IIT Bombay, India TPC Chairs Neminath Hubballi, IIT Indore, India Rakesh Verma, University of Houston, USA Finance Chairs Radha V, IDRBT Hyderabad, India Gourinath Banda, IIT Indore, India Publicity Chairs Bruno Bogaz Zarpelão, State University of Londrina(UEL), Brazil Ashok Kumar Das, IIIT Hyderabad, India Himanshu Agrawal, Curtin University, Australia PhD Forum Chairs Radhika B S, NIT Surathkal, India Manjesh Hanawal, IIT Bombay, India Web Chairs Meenakshi Tripathi, MNIT Jaipur, India Yogendra Singh, IIT Indore, India Tutorial Chairs Bodhisatwa Mazumdar, IIT Indore, India Vivek Balachandran, Singapore Institute of Technology Workshop Chairs Deepak Nadig, Purdue University, USA Smriti Bhatt, Purdue University, USA Industry Forum Chairs Maitreya Natu, TCS, India Paromita Choudhury, CAIR, DRDO, India Organizing Chair Neminath Hubballi, IIT Indore, India Organizing Committee Bodhisatwa Mazumdar, IIT Indore, India Gourinath Banda, IIT Indore, India Soma Saha, PIEMR, India Organizing Executive Committee Venkata Badarla, IIT Tirupati, India Neminath Hubballi, IIT Indore, India Chandrashekar Jatoth, NIT Raipur, India Jayaprakash Kar, LNMIIT Jaipur, India Vishwas Patil, IIT Bombay, India Somnath Tripathy, IIT Patna, India TPC Members Phu H. Phung, University of Dayton, USA Saravanan Vijayakumaran, IIT Bombay, India Sambuddho, IIIT Delhi, India Indrajit Ray, Colorado State University, USA Rajan M A, TCS Research, India Maniklal Das, DA-IICT Gandhinagar, India Indrakshi Ray, Colorado State University, USA Luigi V. Mancini, Sapienza University of Rome, Italy Anoop Singhal, NIST, USA Somitra Sanadhya, IIT Jodhpur, India K Gopinath, Rishihood University, India Vinay J. Ribeiro, IIT Bombay, India Ayantika Chatterjee, IIT Kharagpur, India Claudio Agostino Ardagna, Università degli Studi di Milano, Italy Sanjit Chatterjee, IISc Bangalore, India Sandeep Shukla, IIT Kanpur, India Pierangela Samarati, Università degli Studi di Milano, Italy David Marchette, Naval Surface Warfare Center, USA Ram Krishnan, UT San Antonio, USA Vivek Balachandran, Singapore Institute of Technology, Singapore Elisa Bertino, Purdue University, USA Bhavani Thuraisingham, UT Dallas, USA Venkat Venkatakrishnan, Univ. of Illinois, Chicago, USA Somnath Tripathi, IIT Patna, India Shuhui Grace Yang, Purdue University Northwest, USA